depopulate

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de|popu|late /d'iːp'ɒpjʊleɪt/ (depopulates depopulating depopulated)
[VERB] V n
To depopulate an area means to greatly reduce the number of people living there.
The famine threatened to depopulate the continent.
● depopulated [ADJ]
...a small, rural, and depopulated part of the south-west.
● depopulation [N-UNCOUNT]
...rural depopulation.

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